Home

Mikelanj İddiasız kaide overall mutation load vs incidence of p53 mutations ziyaretçi Uzak tarla

TP53 mutations as potential prognostic markers for specific cancers:  Analysis of data from The Cancer Genome Atlas and the International Agency  for Research on Cancer TP53 Database | bioRxiv
TP53 mutations as potential prognostic markers for specific cancers: Analysis of data from The Cancer Genome Atlas and the International Agency for Research on Cancer TP53 Database | bioRxiv

Mutant p53 exerts a dominant negative effect by preventing wild-type p53  from binding to the promoter of its target genes | Oncogene
Mutant p53 exerts a dominant negative effect by preventing wild-type p53 from binding to the promoter of its target genes | Oncogene

Targeting Cavity-Creating p53 Cancer Mutations with Small-Molecule  Stabilizers: the Y220X Paradigm | ACS Chemical Biology
Targeting Cavity-Creating p53 Cancer Mutations with Small-Molecule Stabilizers: the Y220X Paradigm | ACS Chemical Biology

Implications of driver genes associated with a high tumor mutation burden  identified using next‑generation sequencing on immunotherapy in  hepatocellular carcinoma
Implications of driver genes associated with a high tumor mutation burden identified using next‑generation sequencing on immunotherapy in hepatocellular carcinoma

Therapeutic targeting of p53: all mutants are equal, but some mutants are  more equal than others | Nature Reviews Clinical Oncology
Therapeutic targeting of p53: all mutants are equal, but some mutants are more equal than others | Nature Reviews Clinical Oncology

Therapeutic targeting of mutant p53 in pediatric acute lymphoblastic  leukemia | Haematologica
Therapeutic targeting of mutant p53 in pediatric acute lymphoblastic leukemia | Haematologica

Clinical implications of subclonal TP53 mutations in acute myeloid leukemia  | Haematologica
Clinical implications of subclonal TP53 mutations in acute myeloid leukemia | Haematologica

TP53 oncomorphic mutations predict resistance to platinum‑ and taxane‑based  standard chemotherapy in patients diagnosed with advanced serous ovarian  carcinoma
TP53 oncomorphic mutations predict resistance to platinum‑ and taxane‑based standard chemotherapy in patients diagnosed with advanced serous ovarian carcinoma

Disarming mutant p53 oncogenic function - ScienceDirect
Disarming mutant p53 oncogenic function - ScienceDirect

TP53 alterations of hormone-naïve prostate cancer in the Chinese population  | Prostate Cancer and Prostatic Diseases
TP53 alterations of hormone-naïve prostate cancer in the Chinese population | Prostate Cancer and Prostatic Diseases

Five‐year overall survival rate in patients with oncomorphic and... |  Download Scientific Diagram
Five‐year overall survival rate in patients with oncomorphic and... | Download Scientific Diagram

Analysis of P53 mutations and their expression in 56 colorectal cancer cell  lines | PNAS
Analysis of P53 mutations and their expression in 56 colorectal cancer cell lines | PNAS

IJMS | Free Full-Text | Targeting the Oncogenic p53 Mutants in Colorectal  Cancer and Other Solid Tumors | HTML
IJMS | Free Full-Text | Targeting the Oncogenic p53 Mutants in Colorectal Cancer and Other Solid Tumors | HTML

Frontiers | Mutation-Derived Neoantigens for Cancer Immunotherapy
Frontiers | Mutation-Derived Neoantigens for Cancer Immunotherapy

Mutant p53 drives the loss of heterozygosity by the upregulation of Nek2 in  breast cancer cells | Breast Cancer Research | Full Text
Mutant p53 drives the loss of heterozygosity by the upregulation of Nek2 in breast cancer cells | Breast Cancer Research | Full Text

High prevalence and allele burden-independent prognostic importance of p53  mutations in an inner-city MDS/AML cohort | Leukemia
High prevalence and allele burden-independent prognostic importance of p53 mutations in an inner-city MDS/AML cohort | Leukemia

Zinc shapes the folding landscape of p53 and establishes a pathway for  reactivating structurally diverse cancer mutants | eLife
Zinc shapes the folding landscape of p53 and establishes a pathway for reactivating structurally diverse cancer mutants | eLife

LRP1B or TP53 mutations are associated with higher tumor mutational burden  and worse survival in hepatocellular carcinoma
LRP1B or TP53 mutations are associated with higher tumor mutational burden and worse survival in hepatocellular carcinoma

The impact of TP53 mutations and TP53 deletions on survival varies between  AML, ALL, MDS and CLL: an analysis of 3307 cases | Leukemia
The impact of TP53 mutations and TP53 deletions on survival varies between AML, ALL, MDS and CLL: an analysis of 3307 cases | Leukemia

The TP53 mutation rate differs in breast cancers that arise in women with  high or low mammographic density | npj Breast Cancer
The TP53 mutation rate differs in breast cancers that arise in women with high or low mammographic density | npj Breast Cancer

Mutations of the p53 Gene as a Prognostic Factor in Aggressive B-Cell  Lymphoma | NEJM
Mutations of the p53 Gene as a Prognostic Factor in Aggressive B-Cell Lymphoma | NEJM

TP53 mutation spectrum in primary colorectal cancers. a Proportion of... |  Download Scientific Diagram
TP53 mutation spectrum in primary colorectal cancers. a Proportion of... | Download Scientific Diagram

Frontiers | Promising New Tools for Targeting p53 Mutant Cancers: Humoral  and Cell-Based Immunotherapies
Frontiers | Promising New Tools for Targeting p53 Mutant Cancers: Humoral and Cell-Based Immunotherapies

Cancers | Free Full-Text | TP53 Combined Phenotype Score Is Associated with  the Clinical Outcome of TP53-Mutated Myelodysplastic Syndromes | HTML
Cancers | Free Full-Text | TP53 Combined Phenotype Score Is Associated with the Clinical Outcome of TP53-Mutated Myelodysplastic Syndromes | HTML